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This Concept Map, created with IHMC CmapTools, has information related to: E. coli types, freq cause of traveler's diarrhea? E. coli infx mostly ETEC ETEC enterotoxigenic heat-stable toxins & labile toxins (enterotoxins) => incrsd fluid secrtn, ETEC enterotoxigenic heat-stable toxins & labile toxins (enterotoxins) => incrsd fluid secrtn char toxin sim to cholera toxin incb 2d dur ɝd, in large intestine. WBC's? yes EIEC enteroinvasive WBC's from localized infection, non-inflammatory diarrhea something wrong here no ETEC enterotoxigenic heat-stable toxins & labile toxins (enterotoxins) => incrsd fluid secrtn, pile up on & destroy epi causing malabsp. IL-8 EAEC enteroaggregative traveler's, IL-8, RBC's in stool? yes in large intestine. WBC's?, in small intestine WBC? no ETEC enterotoxigenic heat-stable toxins & labile toxins (enterotoxins) => incrsd fluid secrtn, non-inflammatory diarrhea something wrong here yes EPEC enteropathic IL-8, epidemic infantile no EAEC enteroaggregative traveler's, IL-8, EHEC enterohemorrhagic (Shiga-like cytotoxin) can be inflmmtry 2-8% HUS complication hemolytic anemia syndrome - Mostly extremes of age - Microangiopathic hemolytic anemia, thrombocytopenia, renal failure, in small intestine WBC? few epidemic infantile, red box - "inflammatory" other bacteria causes Campylobacter jejuni -colon Salmonella - lower ileum Shigella Yersinia enterocolitica Vibrio parahemolyticus Clostridium difficile, EHEC enterohemorrhagic (Shiga-like cytotoxin) can be inflmmtry cytotoxin destroys protein synthesis, RBC's in stool? no in small intestine WBC?, freq cause of traveler's diarrhea? E. coli infx mostly ETEC EAEC enteroaggregative traveler's, IL-8, pile up on & destroy epi causing malabsp. IL-8 EPEC enteropathic IL-8, in large intestine. WBC's? no EHEC enterohemorrhagic (Shiga-like cytotoxin) can be inflmmtry, EHEC enterohemorrhagic (Shiga-like cytotoxin) can be inflmmtry char mjr resevoir: cattle bloody diarrhea renal failure O157:H7 most prominent serotype, epidemic infantile yes EPEC enteropathic IL-8